ODCs

Click node...

Mitochondrial nonsyndromic sensorineural deafness with susceptibility to aminoglycoside exposure

1 OMIM reference -
5 associated genes
No signs/symptoms info

PROTEIN INTERACTIONS: 1

Autosomal dominant spastic paraplegia type 13

1 OMIM reference -
1 associated gene
No signs/symptoms info

Mitochondrial nonsyndromic sensorineural deafness with susceptibility to aminoglycoside exposure

Autosomal dominant spastic paraplegia type 13

MT-CO1	(UniProt - OMIM)	HSPD1	(UniProt - OMIM)
MT-ND4	(UniProt - OMIM)
MT-RNR1	(OMIM)
MT-TS1	(OMIM)
TRMU	(UniProt - OMIM)


INTERACTOME ASSOCIATIONS (click on a score value to see the evidence)	MT-CO1	(0.55)	HSPD1

Citations in the biomedical literature:

Mitochondrial nonsyndromic sensorineural deafness with susceptibility to aminoglycoside exposure		Autosomal dominant spastic paraplegia type 13
	Synonym(s): - Mitochondrial isolated neurosensory deafness with susceptibility to aminoglycoside exposure - Mitochondrial isolated neurosensory hearing loss with susceptibility to aminoglycoside exposure - Mitochondrial isolated sensorineural deafness with susceptibility to aminoglycoside exposure - Mitochondrial isolated sensorineural hearing loss with susceptibility to aminoglycoside exposure - Mitochondrial nonsyndromic neurosensory deafness with susceptibility to aminoglycoside exposure - Mitochondrial nonsyndromic neurosensory hearing loss with susceptibility to aminoglycoside exposure - Mitochondrial nonsyndromic sensorineural hearing loss with susceptibility to aminoglycoside exposure		Synonym(s): - SPG13

	Classification (Orphanet): - Inborn errors of metabolism - Rare genetic disease - Rare otorhinolaryngologic disease		Classification (Orphanet): - Rare genetic disease - Rare neurologic disease

	Classification (ICD10): (no data available)		Classification (ICD10): - Diseases of the nervous system -

	Epidemiological data: Class of prevalence: unknown Average age onset: variable Average age of death: - Type of inheritance: mitochondrial inheritance		Epidemiological data: Class of prevalence: <1 / 1 000 000 Average age onset: - Average age of death: - Type of inheritance: autosomal dominant

	External references: 1 OMIM reference - No MeSH references		External references: 1 OMIM reference - 1 MeSH reference: C537485

No signs/symptoms info available.